Does titration of anaesthesia using population-derived EEG indices overdose older patients?
Where this comes from
- Record sourced from PubMed, PMID 40000278.
- Also identified by DOI 10.1016/j.bja.2025.01.002 and PMC identifier 11947554.
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Abstract
Compared with the young, the older patient group has increased high-frequency EEG power whilst under volatile general anaesthesia. This increased high-frequency power elevates the spectral entropy values above the recommended range. Thus, aggressive titration of general anaesthesia with volatile agents to achieve entropy values of 40-60 in older patients will commonly result in overdose, as manifest by burst suppression.
Medical subject headings
- Electroencephalography
- Drug Overdose
- Anesthesia, General
- Anesthetics, Inhalation