18 F-FDG PET/CT Positive and 68 Ga-DOTA-Bombesin PET/CT Negative Focus of Benign Apocrine Metaplasia Mimicking Malignancy.

Arslan, Esra; Baloğlu, Mehmet Can; Özkan, İrem Aylin; Alçin, Göksel; Akgün, Elife; Çermik, Tevfik Fikret · Clin Nucl Med · 2025

case_report · Level V

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Abstract

Gastrin-releasing peptide receptor (GRPR) is a promising agent for imaging and development of theranostic radioligands in estrogen receptor (ER)-positive luminal type breast cancer (BC) and may show expression not only in primary malignant lesions but also in lymph node metastases and distant organ metastases. We would like to present a lesion diagnosed as benign apocrine metaplasia in a 45-year-old woman diagnosed with BC, which was negative in 68 Ga-DOTA-Bombesin PET-CT and false positive in 18 F-FDG PET-CT imaging, within the scope of the ongoing study.

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