Unexpected Extrarenal Uptake of 99m Tc-DTPA in Renal Scintigraphy: Insights From Two Cases of Adrenal Tumors.

Han, Yanmei; Huang, Daijuan; Gao, Zairong; Xia, Xiaotian · Clin Nucl Med · 2025

case_report · Level V

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Abstract

Renal dynamic scintigraphy is a crucial diagnostic tool for assessing renal function, yet unexpected findings can provide additional insights into extrarenal conditions. We report 2 rare cases of extrarenal 99m Tc-DTPA uptake associated with adrenal tumors: one adrenal cortical carcinoma and one pheochromocytoma. In both cases, significant tracer accumulation in the adrenal region was observed, highlighting an uncommon but noteworthy diagnostic consideration. These cases emphasize the importance of including adrenal tumors in the differential diagnosis when encountering abnormal 99m Tc-DTPA uptake patterns, offering valuable clinical insights for interpreting atypical imaging findings and broadening diagnostic perspectives.

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