Mpox in a Patient With a Signal Transducer and Activator of Transcription 1 Gain-of-Function Mutation.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 40044363.
- Also identified by DOI 10.1016/j.mayocp.2024.11.022.
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Abstract
We report a case of mpox in a patient with a signal transducer and activator of transcription 1 gain-of-function mutation. Despite initial improvement with intravenous immune globulin and tecovirimat, severe symptoms developed and the patient died. This underscores the need for immune system optimization and effective virucidal treatments for mpox.
Medical subject headings
- Gain of Function Mutation
- Mpox, Monkeypox
- STAT1 Transcription Factor