Autologous cells, no longer lost in translation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40054453.
- Also identified by DOI 10.1016/j.stem.2025.02.004.
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Abstract
In 2020, a case report described autologous transplantation of iPSC-derived dopamine (DA) neurons in a Parkinson's disease (PD) patient.<sup>1</sup> The team now follows up with the pre-clinical safety and efficacy data of autologous iPSC-derived DA neurons, forming the basis for regulatory approval of a phase 1 clinical trial involving 8 patients.<sup>2</sup>.
Medical subject headings
- Dopaminergic Neurons
- Parkinson Disease
- Induced Pluripotent Stem Cells
- Translational Research, Biomedical