Development and Evaluation of a Novel Algorithm to Identify Doxycycline Postexposure Prophylaxis Users at a Large Healthcare System in the Bronx, New York.

Mullis, Caroline E; Bishop, Derek; Fazzari, Melissa; Tappen, Nataliya; Felsen, Uriel; Meyerowitz, Eric A · Clin Infect Dis · 2026

other · Level IV

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Abstract

Doxycycline postexposure prophylaxis (doxy-PEP) is used to prevent chlamydia, syphilis, and gonorrhea infections in sexual and gender minority men and transgender women. We describe a systematic process for developing algorithms that allow for the identification of doxy-PEP prescriptions. Using an identified algorithm will allow improved monitoring of implementation and effectiveness.

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