Assessing Mucosal Recovery During the First 15 Months of Adopting a Gluten-Free Diet in Children With Celiac Disease.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 40084739.
- Also identified by DOI 10.14309/ajg.0000000000003400 and PMC identifier 12208375.
- Licence recorded as CC BY-NC-ND.
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Abstract
Determine contemporary rates of early mucosal recovery in children with celiac disease (CeD). Multicenter retrospective cohort study in Canada and the United States. Children diagnosed with CeD between 2016 and 2021 who underwent a follow-up biopsy within 15 months of diagnosis were included. Overall, 96 of 130 children (74%) had mucosal recovery, including 48% children (12/25) who were assessed within 3 months. Musculoskeletal symptoms at diagnosis were the only clinical characteristic associated with persistent enteropathy. While mucosal recovery can occur within months, more than a quarter of children with CeD had persistent enteropathy within 15 months of treatment.
Medical subject headings
- Celiac Disease
- Diet, Gluten-Free
- Intestinal Mucosa