PSMA-Uptake Reveals Globet Cell Cancer of the Appendix in a Patient Staged for Prostate Cancer With PET/CT.

Lampe, Nina A; Anzic, Nina; Stürmlin, Joe; Strobel, Klaus; Grünig, Hannes · Clin Nucl Med · 2025

case_report · Level V

Where this comes from

Abstract

18 F-PSMA 1007 is an established tracer for staging intermediate and high-risk prostate cancer. Besides prostate cancer cells, benign tumors and inflammations/infections can show unspecific PSMA uptake. We present a case of incidental PSMA uptake of the appendix revealing a globet cell adenocarcinoma in histology after surgical resection. Globet cell tumors are rare neoplasms of the appendix. Patients with incidental PSMA uptake in the appendix should undergo further work-up.

Medical subject headings