The intraoperative SEEG and <sup>18</sup>FDG-PET tailored temporal lobe resection (iSP-TR) for the tissue-spearing surgical treatment of drug-resistant mesial temporal lobe epilepsy: how we do it.
Where this comes from
- Record sourced from PubMed, PMID 40106065.
- Also identified by DOI 10.1007/s00701-025-06491-x and PMC identifier 11922984.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
For drug-resistant mesial temporal lobe epilepsy (MTLE), surgery is recommended. There is no evidence of a seizure outcome advantage of temporal lobectomy over other strategies despite the high risks of this surgical procedure. We describe a Temporal Resection guided by intraoperative stereo-electroencephalography (iSEEG) and the <sup>18</sup>FluoroDeoxyGlucose PET (<sup>18</sup>FDG PET) (iSP-TR) to treat lesional MTLE. We avoided functional cortical areas using navigated Transcranial Magnetic Stimulation (nTMS). iSP-TR allows for a spare brain parenchyma compared to temporal lobectomy without compromising seizure outcomes.
Medical subject headings
- Anterior Temporal Lobectomy
- Drug Resistant Epilepsy
- Electroencephalography
- Epilepsy, Temporal Lobe
- Neurosurgical Procedures
- Positron-Emission Tomography
- Temporal Lobe