Patient-reported quality of life and aesthetic satisfaction continues to improve for 1-year after Mohs surgery: A multicenter prospective cohort study.

Veldhuizen, Inge J; Dusza, Stephen W; Kuo, Alyce; Aleisa, Abdullah; Blue, Elliot; Adhikari, Sushmita; Nadir, Umer; Le, Kim et al. · J Am Acad Dermatol · 2025

prospective_cohort · Level II

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Abstract

Despite the growth in patient-centered care, multicenter prospective studies investigating satisfaction after skin cancer surgery are limited. To assess trends in esthetic satisfaction, symptoms, and quality of life over 1 year in facial skin cancer patients. Patients with facial skin cancer who underwent surgery were enrolled at 4 hospitals across the United States. A total of 990 patients were included. The FACE-Q Skin Cancer questionnaire was administered before surgery, at 2-week, 6-month, and 1-year intervals postsurgery. Patients reported increased satisfaction with FACE-Q scales over 1 year. Significant factors influencing outcomes included sex, age, history of facial skin cancer, cosmetic surgery, defect size, and cancer location. Males reported higher satisfaction with appearance (P = .003) and scar (P < .001), and reduced psychosocial distress (P < .001). Larger defects were associated with greater psychosocial distress (P = .037) and lower scar appraisal (P = .008). Patients with nose skin cancer reported lower satisfaction with appearance and scars (P = .026, P < .001), higher psychosocial distress (P = .004), and increased cancer worry (P = .045). Patients with cancer near the eyes reported increased cancer worry (P = .004). Reconstruction types did not influence satisfaction. Clinical and patient characteristics significantly influence patient-reported outcomes, highlighting the need for personalized treatment approaches to optimize outcomes in dermatologic surgery.

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