Matching Human Expertise: ChatGPT's Performance on Hand Surgery Examinations.

Kirschenbaum, Zachary A; Han, Yuri; Vrindten, Kiera L; Wang, Hanbin; Cody, Ron; Katt, Brian M; Kirschenbaum, David · Hand (N Y) · 2025

cross_sectional · Level IV

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Abstract

The integration of artificial intelligence (AI) into health care witnessed significant advancements, particularly with AI-driven tools like ChatGPT. Initial evaluations indicated that ChatGPT 3.5 did not perform as well as humans on specialized hand surgery self-assessment examinations. The purpose of this study is to evaluate the performance of ChatGPT 4o on American Society for Surgery of the Hand (ASSH) self-assessment questions and whether using enhanced techniques such as better prompts and file search improve accuracy. Using data from the ASSH self-assessment examinations (2008-2013), we explored the impact of ChatGPT model version, prompt, and file search on the accuracy of AI-generated responses. We used OpenAI's application programming interface to automate question input and response scoring. Statistical analysis was conducted using one-way analysis of variance. KR-20 was used to assess the reliability of the test. Results indicate that the latest AI models, particularly ChatGPT 4o with enhanced prompting and access to peer-reviewed literature, can achieve performance levels comparable to human examinees, particularly on text-based questions. ChatGPT 4o performed significantly better than ChatGPT 3.5 and showed marked improvement with better prompts and file search capabilities. The KR-20 for the 2013 examination was 0.946, indicating a very reliable test. These findings highlight AI's potential to support medical education and practice, demonstrating that ChatGPT can perform at a human-equivalent level on hand surgery self-assessment examinations. Our results suggest potential utility as a supplementary tool in educational settings and as a supportive resource in clinical practice.

Anatomy