Glucocorticoids, Concomitant Immunosuppression, and Pneumocystis jirovecii Pneumonia Prophylaxis Among US Adults.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 40117207.
- Also identified by DOI 10.1093/cid/ciaf147.
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Abstract
The impact of glucocorticoids, comorbid conditions, and immunosuppressive therapies on Pneumocystis jirovecii pneumonia risk remains understudied, and prophylaxis is underused. Among US adults in TriNetX prescribed glucocorticoids for ≥2 weeks, 44.6% received >20 mg prednisone equivalents daily. Prophylaxis rates were low, with higher glucocorticoid doses associated with lower prophylaxis odds.
Medical subject headings
- Pneumonia, Pneumocystis
- Pneumocystis carinii
- Glucocorticoids
- Immunosuppressive Agents
- Antibiotic Prophylaxis