SnapShot: Human sperm-egg interface proteins.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40118033.
- Also identified by DOI 10.1016/j.cell.2025.01.001.
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Abstract
Human fertilization is a complex, highly regulated process that involves intricate molecular interactions between sperm and egg. Ultimately, this process culminates in the fusion of the gamete membranes to form a zygote. Gene disruption studies in mice have identified several critical fertilization factors. This SnapShot highlights the structure function of key proteins at the sperm-egg interface, providing insights into the mechanism of fertilization. To view this SnapShot, open or download the PDF.
Medical subject headings
- Sperm-Ovum Interactions
- Spermatozoa
- Ovum