Isotretinoin use, mood changes and suicidality. What is the link?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 40123468.
- Also identified by DOI 10.1192/bjp.2025.26.
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Abstract
For over four decades, isotretinoin has shown unparalleled efficacy in the management of severe recalcitrant acne. However, controversies exist about its psychiatric safety profile. This editorial discusses the alleged causal role of isotretinoin in the development of psychiatric adverse events in light of the best available evidence.
Medical subject headings
- Isotretinoin
- Acne Vulgaris
- Dermatologic Agents
- Suicide
- Mood Disorders