Secondary Pulmonary Hypertrophic Osteoarthropathy Detected on [ 68 Ga]Ga-FAPI-46 PET/CT.
case_report · Level V
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- Record sourced from PubMed, PMID 40128945.
- Also identified by DOI 10.1097/RLU.0000000000005859.
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Abstract
A 55-year-old man presented with arthralgia, digital clubbing, and pitting edema. A suspicious pulmonary mass showed high tracer uptake on both [ 18 F]FDG and [ 68 Ga]Ga-FAPI-46 PET/CT. Remarkably, FAPI PET revealed a diffuse periosteal tracer uptake of the long bones, highly suggestive for hypertrophic osteoarthropathy. The secondary and paraneoplastic nature of this condition was confirmed after a biopsy of the pulmonary mass. Hypertrophic osteoarthropathy is characterized by the clinical symptoms of arthralgia, digital clubbing, and periostosis, and is associated with malignancy in 90% of cases.
Medical subject headings
- Osteoarthropathy, Secondary Hypertrophic
- Positron Emission Tomography Computed Tomography