Nanocomposite Hydrogels and Micro/Nanostructures for Printing Organoids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40162603.
- Also identified by DOI 10.1021/acsnano.4c17587.
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Abstract
Organoids are 3D artificial miniature organs composed of a cluster of self-renewing and self-organizing cells <i>in vitro</i>, which mimic the functions of real organs. Nanotechnologies, including the preparation of nanomaterials and the fabrication of micro/nanostructures, have been proven to promote cell proliferation, guide cell differentiation, and regulate cell self-organization, showing great promise in engineering organoids. In this Perspective, different types of nanocomposite hydrogels for organoid culture are summarized, the effects of micro/nanostructures on organoid growth and development are discussed, and 3D bioprinting technologies for constructing organoid models are introduced.
Medical subject headings
- Bioprinting
- Hydrogels
- Nanocomposites
- Nanostructures
- Organoids
- Printing, Three-Dimensional