Can we talk? The cryptic communications of hepatic stellate cells in lipid metabolism.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 40174572.
- Also identified by DOI 10.1016/j.cmet.2025.03.008.
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Abstract
The contributions of signals generated by hepatic stellate cells that regulate hepatocyte lipid and glucose homeostasis are largely unexplored. The article by Hansen et al. introduces a novel role of plasmalemma vesicle-associated protein (PLVAP), a membrane protein expressed by hepatic stellate cells, in regulating these pathways in hepatocytes during fasting.
Medical subject headings
- Hepatic Stellate Cells
- Lipid Metabolism
- Membrane Proteins
- Cell Communication