Immune repertoire profiling uncovers pervasive T cell clonal expansions in benign prostatic hyperplasia.

Pollack, Anna S; Kunder, Christian A; Ho, Chandler C; Chou, Josephine; Pollack, Andrew J; Geisick, Rachel Lp; Zhang, Bing M; West, Robert B et al. · J Clin Invest · 2025

basic_science · Level V

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Abstract

We discovered T-cell clonal expansions in benign prostatic hyperplasia, indicative of a specific adaptive immune response and with implications for disease pathogenesis and new treatments.

Medical subject headings