Rosai-Dorfman Disease Mimicking Metastasis to the Spleen From Breast Cancer.

Hooda, Zamaan; Lu, Yang; Mehran, Reza John; Moran, Cesar; Barcenas, Carlos Hernando · Clin Nucl Med · 2025

case_report · Level V

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Abstract

Rosai-Dorfman disease is a non-Langerhans cell histiocytosis with ubiquitous distribution. Although more common in lymph nodes, it has been described in many organ systems. The current case depicts a 54-year-old woman with a history of estrogen receptor-positive breast carcinoma who showed different image features of metastatic lymph nodes and splenic Rosai-Dorfman disease on FDG and FES PET/CT scans.

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