Unilateral Parotid Gland Involvement of Relapsed Acute Lymphoblastic Leukemia Demonstrated by 18F-FDG PET/CT.

Yao, Xilan; Wang, Hongrong; Lei, Xiao; Yang, Jigang · Clin Nucl Med · 2025

case_report · Level V

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Abstract

The involvement of the parotid gland by acute lymphoblastic leukemia in extramedullary relapse is considered a rare occurrence. A 5-year-old girl with acute lymphoblastic leukemia presented with peripheral facial paralysis, and her symptoms remained unrelieved despite symptomatic treatment. 18F-FDG PET/CT showed hypermetabolic activity not only in the left parotid gland but also in multiple cervical lymph nodes, confirming a relapse of T-cell acute lymphoblastic leukemia.

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