Engineered heart tissue patches: A milestone in cardiac regenerative medicine.

van Mil, Alain; Janssen, Jasmijn; van Rooij, Eva · Cell Stem Cell · 2025

case_series · Level IV

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Abstract

Researchers have demonstrated that a stem cell-derived heart muscle patch can safely remuscularize failing hearts.<sup>1</sup> Published in Nature, the study shows successful long-term cardiac integration of a patch in a primate model and a human patient with no adverse effects. This breakthrough marks a major step toward regenerative therapies for advanced heart failure.

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