Tubarial gland sparing for oropharyngeal cancer: Feasibility with intensity modulated proton therapy & intensity modulated radiation therapy.

Yarlagadda, Sreenija; Rohe, Robert M; McNeill, Valeriane; Nemec, Joanna R; Tohtz, Chelsea P; Fellows, Zachary W; McAllister, Nicole; Rzepczynski, Amy E et al. · Radiother Oncol · 2025

basic_science · Level V

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Abstract

The feasibility of sparing tubarial glands in oropharyngeal radiotherapy was assessed using IMPT and IMRT. Tubarial gland absolute mean dose differences of up to 18 Gy were observed between clinical and re-optimized plans without compromising target coverage. IMPT plans met tubarial gland mean dose constraints more often than IMRT plans.

Medical subject headings