Pelvic Lymph Node Dissection in Prostate Cancer: Evidence and Implications.

Roberts, Matthew J; Gandaglia, Giorgio; Oprea-Lager, Daniela E; Stranne, Johan; Cornford, Philip; Tilki, Derya; EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines Panel · Eur Urol · 2025

review · Level V

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Abstract

The role of extended pelvic lymph-node dissection (ePLND) in prostate cancer has been revisited in light of evidence from studies on staging via prostate-specific membrane antigen positron emission tomography/computed tomography. It is difficult to predict which individuals might benefit from ePLND. Patients should be counselled about this uncertainty and the risks of ePLND-associated morbidity as part of the shared decision-making process.

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