Long-term effects of a primary school-based overweight preventive intervention on physical fitness and physical activity: a propensity score-matched retrospective cohort study within the Generation R Study.

Smit, Michel Sebastiaan; Mölenberg, Famke; Mensink-Bout, Rosalie; Nieboer, Daan; Voortman, Trudy; Duijts, Liesbeth; Raat, Hein; Jansen, Wilma · BMJ Open · 2025

retrospective_cohort · Level III

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Abstract

In this study, we evaluate the long-term effects (±1.5 years postintervention) of 6-year exposure to the Lekker Fit! intervention on physical fitness and physical activity (PA). The retrospective intervention evaluation is embedded within the Generation R Study in Rotterdam, the Netherlands, a population-based prospective birth cohort study. Measurements took place in the research centre of the Generation R cohort study. 5489 adolescents from the Generation R Study were eligible for inclusion within this study. Successful linking to school career data was possible for 4129 adolescents who were then retrospectively subdivided into a Lekker Fit! group, mixed group and regular school group based on their primary school career. The Lekker Fit! intervention is a multicomponent primary school-based intervention for the prevention of overweight. It focuses on a healthy diet and healthy lifestyle rather than focusing directly on the reduction of overweight. The intervention targets individual behaviour of children as well as their obesogenic environment and parental engagement in shaping their children's behaviour. Aged 13/14 years old, physical fitness was measured with an incremental ergometer test. The actual highest achieved work rate was divided by the expected highest achieved work rate (age- and sex-related Dutch population-based reference data), and converted into z-scores. PA was determined by the number of days with at least 1 hour of PA, obtained by a self-reported questionnaire. Propensity score matching was performed to correct for non-random selection bias. Linear regression analyses were performed to estimate intervention effects. Children from the Lekker Fit! group had significantly lower fitness z-scores (-0.18 (95% CI -0.29 to -0.06), n=1826) compared with children from the matched regular school group. No Lekker Fit! intervention effect was found on PA (-0.12 (95% CI -0.36 to 0.12), n=1258). No evidence was found for long-term favourable effects of a school-based multicomponent intervention on physical fitness and PA. Recommendations for policy and future research are discussed.

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