Mixed adeno-neuroendocrine carcinoma on dual-tracer 18 F-FDG and 68 Ga-DOTATATE PET/CT.

Lin, Xuezhi; Zhang, Guojian · Clin Nucl Med · 2025

case_report · Level V

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Abstract

Tumor heterogeneity is not effortlessly detected. We present the case of a 66-year-old man with a history of rectal adenocarcinoma diagnosed four years ago, where mixed adeno-neuroendocrine carcinoma were identified via dual-tracer 18 F-FDG and 68 Ga-DOTATATE PET/CT. This case highlights the value of dual-tracer PET/CT imaging in assessing tumor heterogeneity and compensating for potential pathological sampling bias.

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