Vaccinology in the artificial intelligence era.

Gasperini, Gianmarco; Baylor, Norman; Black, Steve; Bloom, David E; Cramer, Jakob; de Lannoy, Gaël; Denoel, Philippe; Feinberg, Mark et al. · Sci Transl Med · 2025

review · Level V

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Abstract

Artificial intelligence (AI) has already transformed vaccine antigen design and could transform the entire vaccinology pipeline, including immune responses and emerging infectious disease prediction, manufacturing and regulatory processes, clinical trial design and implementation, and vaccine access and equity. However, realizing the promise of AI for vaccinology requires more high-quality data.

Medical subject headings