Importance of cohort and target trial emulation in clinical research.

Liang, Xiaohua; Zhang, Di; Wang, Huan; Tahir, Muhammad Fahad; Chen, Lanling; Zhao, Xiaodong; Zou, Zhiyong · Cell Rep Med · 2025

review · Level V

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Abstract

Advances in cohort studies and target trial emulation provide substantial evidence for policymaking to enhance global health. Moving forward, key priorities should focus on standardizing data processing protocols, advancing life-course research, establishing global health data-sharing platforms, and integrating population studies with omics research to support disease prevention and treatment development.

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