Occupational Exposure of Healthcare Workers During Drug Reconstitution and Handling Tasks: A Multicenter Assessment at Dutch Hospital Wards.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 40245409.
- Also identified by DOI 10.1097/JOM.0000000000003401 and PMC identifier 12237139.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
This study evaluated healthcare workers' occupational exposure to inhaled drugs during drug reconstitution and handling tasks, focusing on compliance with occupational exposure limits (OELs). Ten nurses and pharmacy technicians were monitored during an 8-hour shift to measure inhalable particle concentrations using a portable sampling device. Inhalable particle concentrations ranged from <15 to 381 μg/m 3 (arithmetic mean 83 μg/m 3 ). Exposure to drugs in hazardous drug classes (HDCs) 1, 2, and 3 complied with OELs, while exposure to drugs in HDCs 4 and 5 exceeded OELs, highlighting the need for enhanced protective measures. No additional precautions are needed for drugs in HDCs 1, 2, and 3, but dust exhaust or biosafety cabinets are recommended for handling drugs in HDCs 4 and 5.
Medical subject headings
- Occupational Exposure
- Inhalation Exposure
- Air Pollutants, Occupational
- Drug Compounding