Insulin Autoimmune Syndrome: Imaging Findings and Uptake Pattern With 68 Ga-Exendin-4 and 68 Ga-DOTATATE PET-CT.
case_report · Level V
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- Record sourced from PubMed, PMID 40258371.
- Also identified by DOI 10.1097/RLU.0000000000005916.
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Abstract
A 62-year-old woman who experienced a seizure was found to be hypoglycemic. A prolonged fasting test revealed raised critical insulin and C-peptide levels. CECT of the abdomen demonstrated an isodense focus in the tail of the pancreas. On the suspicion of insulinoma, she was referred for a 68 Ga-Exendin-4 PET/CT study, which revealed diffuse tracer uptake in the entire pancreatic tissue. She also underwent a 68 Ga-DOTATATE PET/CT scan, which demonstrated physiological uptake in the pancreas. She later tested positive for anti-insulin antibodies. We herein report a positive Exendin-4 PET/CT study in a case of insulin autoimmune syndrome with its uptake pattern in this entity.
Medical subject headings
- Positron Emission Tomography Computed Tomography
- Organometallic Compounds
- Insulin
- Autoimmune Diseases
- Peptides
- Venoms