Localized Intense Uptake in the Skull on 18 F-Flortaucipir PET/CT.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 40263752.
- Also identified by DOI 10.1097/RLU.0000000000005848.
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Abstract
18 F-Flortaucipir, as a classical Tau protein visualizer, has been widely used in the diagnosis of neurodegenerative diseases, especially Alzheimer disease. This report describes a case of intense uptake of 18 F-Flortaucipir at 2 sites of reduced bone mineral density in the skull, but no radioactivity uptake was seen on 18 F-FDG and 18 F-Florbetapir PET/CT imaging at the same lesion sites. The mechanism behind 18 F-Flortaucipir uptake in focal osteopenia remains unclear. This study provides evidence for the mechanism of the above phenomenon.
Medical subject headings
- Carbolines
- Positron Emission Tomography Computed Tomography
- Skull