Uncommon Bilateral Frontoparietal Cortex Hypermetabolism Revealed by 18 F-FDG PET/CT in a Patient With Anti-LGI1 Encephalitis.
case_report · Level V
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- Record sourced from PubMed, PMID 40263766.
- Also identified by DOI 10.1097/RLU.0000000000005824.
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Abstract
Limbic hypermetabolism is a frequently observed manifestation of anti-LGI1 encephalitis on 18 F-FDG PET/CT imaging. In this case report, we present an atypical finding on 18 F-FDG PET/CT in a patient with anti-LGI1 encephalitis and negative MRI results. Apart from the expected hypermetabolism in the bilateral limbic system, there was also an uncommon intense uptake of 18 F-FDG noted in the bilateral frontoparietal cortex. Subsequent follow-up scans demonstrated normalized metabolism following treatment. The case highlights that neocortical hypermetabolism can be a characteristic feature of active anti-LGI1 encephalitis on 18 F-FDG PET/CT imaging.
Medical subject headings
- Autoantibodies
- Encephalitis
- Fluorodeoxyglucose F18
- Frontal Lobe
- Parietal Lobe
- Positron Emission Tomography Computed Tomography
- Proteins