Recurrent Solitary Pleural Metastasis Originating From Neuroblastoma as Demonstrated by 123I-MIBG Scan.

Wen, Xin; Lu, Xia; Xu, Yanfeng; Liu, Jun; Yang, Jigang · Clin Nucl Med · 2025

case_report · Level V

Where this comes from

Abstract

An 8-year-old boy with high-risk neuroblastoma underwent routine follow-up 123I-MIBG scan, which revealed abnormal 123I-MIBG accumulation in right pleura, suggestive of potential metastasis. Histopathologic examination of the biopsy specimen confirmed the presence of pleural metastasis. The patient subsequently received four cycles of chemotherapy. A follow-up 123I-MIBG scan after chemotherapy demonstrated no abnormal MIBG uptake, indicating remission of the pleural metastasis. However, 6 months later, a subsequent 123I-MIBG scan revealed recurrent abnormal MIBG uptake in the right pleura at the same location as the initial recurrence. Surgical pathology confirmed the diagnosis of recurrent pleural metastasis.

Medical subject headings