68 Ga FAPI-04 PET/MRI for Detecting Metastatic Bone Lesions of Esophageal Cancer in Patients With G-CSF Administration, Missed by 18 F FDG PET/CT.

Miao, Jingxuan; Su, Xiaoyu; Xu, Alei; Yao, Lei; Wang, Hui · Clin Nucl Med · 2025

case_report · Level V

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Abstract

We report a patient who underwent surgery for esophageal cancer, in whom 18 F FDG PET/CT showed diffuse skeletal uptake, while 68 Ga FAPI-04 PET/MRI revealed significantly higher uptake in bone metastatic lesions. Bone lesions were visible after granulocyte-colony stimulating factor(G-CSF) administration due to lower 68 Ga FAPI-04 background uptake, suggesting its superior potential for detecting bone metastases in esophageal cancer patients after G-CSF treatment.

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