Autonomously Functioning Thyroid Nodule With 99m Tc-PSMA Uptake in a Patient With Prostate Cancer.
case_report · Level V
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- Record sourced from PubMed, PMID 40310014.
- Also identified by DOI 10.1097/RLU.0000000000005853.
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Abstract
We present the findings of a 99m Tc-PSMA scan in a 76-year-old man with a history of prostate cancer. He was referred for re-staging and response to treatment. The 99m Tc-HYNIC PSMA scan incidentally detected an area of increased uptake in the neck region. Subsequent SPECT/CT imaging revealed a large, heterogeneous PSMA-avid thyroid nodule with macrocalcification, suggesting a benign thyroid nodule. Comprehensive imaging confirmed hyperthyroidism with a large autonomously functioning nodule. The case underscores the importance of recognizing PSMA uptake in benign thyroid lesions, emphasizing the need for a thorough evaluation to prevent misdiagnosis and ensure appropriate management.
Medical subject headings
- Prostatic Neoplasms
- Thyroid Nodule
- Organotechnetium Compounds
- Glutamate Carboxypeptidase II
- Antigens, Surface