Exceptional Response to Rechallenge Peptide Receptor Radionuclide Therapy in Metastatic Carotid Body Tumor.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 40310021.
- Also identified by DOI 10.1097/RLU.0000000000005930.
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Abstract
Carotid body tumor (CBT) is the most common head and neck paraganglioma with the very rare occurrence of distant metastases. The widespread distant metastases in head and neck paraganglioma have limited treatment options, with peptide receptor radionuclide therapy (PRRT) being an effective treatment in somatostatin receptor-expressing lesions. Here is a case of a 45-year-old woman with metastatic CBT who showed excellent response initially to 177 Lu-DOTATATE PRRT, but presented later in wheel-chair bound condition with metastatic lesions and spinal cord compression at multiple levels, which again showed exceptional response to rechallenge PRRT.
Medical subject headings
- Carotid Body Tumor
- Receptors, Peptide
- Octreotide