MR-guided Laser Interstitial Thermal Therapy mesencephalotomy for medically intractable malignant pain.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 40314843.
- Also identified by DOI 10.1007/s00701-025-06544-1 and PMC identifier 12048455.
- Licence recorded as CC BY-NC-ND.
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Abstract
Stereotactic mesencephalotomy is a neurosurgical technique designed to sever spinothalamic pain transmission pathways for medically intractable pain. This report presents the first case of Magnetic Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT) mesencephalotomy for severe malignant pain due to metastatic melanoma. The procedure significantly reduced the patient's pain, with a postoperative visual analog scale (VAS) score decreasing from > 7 to < 3. No adverse effects were observed. The case underscores the potential of MRgLITT mesencephalotomy as a precise, minimally invasive option for pain management in palliative care settings.
Medical subject headings
- Cancer Pain
- Laser Therapy
- Magnetic Resonance Imaging
- Melanoma
- Intractable Pain