Synchronization Strategy for Activity and Stability in Fenton-Like Single-Atom Catalysis.

Abstract

Single-atom catalysts (SACs) have garnered significant attention in the applications of environmental remediation based on Fenton-like systems. Current research on Fenton-like single-atom catalysis often emphasizes catalytic activity and mechanism regulation, while paying limited attention to the simultaneous enhancement of both activity and stability-a critical factor for the practical and scale-up applications of SACs. This review systematically summarizes recent advances in synchronization strategies for improving the activity and stability of Fenton-like single-atom catalysis, with a focus on the design principles and mechanisms of four key strategies: coordination engineering, confinement effects, carrier substitution, and catalytic module design. To the best of knowledge, this represents the first comprehensive review of Fenton-like single-atom catalysis from the perspective of concurrent optimization of activity and stability. Additionally, the auxiliary role of machine learning and lifecycle assessment (LCA) is evaluated in advancing these synchronization strategies. By investigating the interplay among different support materials, coordination configurations, and reaction environments, as well as enlarged modules, key factors governing the stability/activity of SACs are highlighted, and future directions are proposed for developing next-generation catalysts with high efficiency and long-term durability for practical environmental remediation.