Prostate Adenocarcinoma Recurrence in the Vas Deferens Unveiled by 99m Tc-PSMA SPECT/CT Imaging.
case_report · Level V
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- Record sourced from PubMed, PMID 40357624.
- Also identified by DOI 10.1097/RLU.0000000000005881.
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Abstract
We present a case involving a 77-year-old man with prostate cancer who underwent radical prostatectomy with negative surgical margins. After 10 years without follow-up, his serum prostate-specific antigen level increased to 2.76 ng/mL, suggesting disease recurrence. Due to limited access to 68 Ga-PSMA PET/CT, a 99m Tc-HYNIC-PSMA SPECT/CT was conducted, which identified PSMA uptake in the bilateral vas deferens, a rare site for recurrence. While recurrence in the vas deferens has been previously reported using 68 Ga-PSMA PET/CT or PET/MR, this novel experience with 99m Tc-PSMA SPECT/CT highlights its potential utility in detecting such recurrences. This is particularly relevant in low-income countries where access to PET/CT may be limited.
Medical subject headings
- Prostatic Neoplasms
- Adenocarcinoma
- Single Photon Emission Computed Tomography Computed Tomography
- Vas Deferens
- Positron Emission Tomography Computed Tomography
- Neoplasm Recurrence, Local
- Organotechnetium Compounds