Hepatic Eosinophilic Granuloma Mimicking Liver Metastases of Unknown Primary Focus on 18 F-FDG and 68 Ga-FAPI PET/CT.

Dai, Meng; Yang, Kai; Zhao, Xiujuan; Zhang, Jingmian; Zhao, Xinming · Clin Nucl Med · 2026

case_report · Level V

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Abstract

A 53-year-old man presented with right upper abdominal pain for more than 3 weeks without an apparent cause. Multiple sequences of MR imaging detected multiple liver nodules with irregular peripheral enhancement. 18 F-FDG and 68 Ga-FAPI PET showed multiple elevated tracer uptake, which mimicked multiple liver metastases of unknown primary focus. Finally, the pathology of ultrasound-guided biopsy confirmed the diagnosis of hepatic eosinophilic granuloma (HEG).

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