Maximal Oxygen Uptake and Coronary Artery Calcium Scores in Firefighters.

Li, Mingyue; Han, Jiali; Muegge, Carolyn; Zollinger, Terrell; Zhou, Laura Y; Monahan, Patrick; Phillips, Hallie Jo; Wessel, Jennifer et al. · J Occup Environ Med · 2025

cross_sectional · Level IV

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Abstract

This study investigates the association between maximal oxygen uptake (VO 2 max) and coronary artery calcium (CAC) scores in Indiana firefighters across different age groups. Using cross-sectional data, multivariable linear regression was conducted to examine the relationship between VO 2 max and CAC, stratified by age (<45 and ≥45 years), with adjustments for cardiovascular risk factors. Higher VO 2 max was significantly associated with lower CAC scores in firefighters aged ≥45 years (β = -7.30; 95% CI: -11.41, -3.18; P < 0.001). No association was detected in firefighters under 45 years. Differences may reflect unique occupational physical demands and age specific cardiovascular risk profiles. Higher aerobic fitness is linked to reduced subclinical atherosclerosis in older firefighters, underscoring the importance of maintaining fitness to mitigate cardiovascular risks in this high risk group.

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