18 F-FDG PET/CT and 68 Ga-Pentixafor PET/CT Findings of Gastric Mucosa-associated Lymphoid Tissue Lymphoma Transformation to Diffuse Large B-cell Lymphoma.
case_report · Level V
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- Record sourced from PubMed, PMID 40367498.
- Also identified by DOI 10.1097/RLU.0000000000005957.
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Abstract
A 66-year-old man with a pathology-confirmed gastric mucosa-associated lymphoid tissue (MALT) lymphoma underwent imaging with both 68 Ga-pentixafor and 18 F-FDG PET/CT. The 18 F-FDG PET/CT demonstrated intense FDG uptake in the gastric lesion, whereas the 68 Ga-pentixafor PET/CT showed only minimal tracer uptake. Subsequent histopathologic evaluation confirmed a transformation into aggressive diffuse large B-cell lymphoma (DLBCL). This case underscores the importance of recognizing atypical imaging patterns to identify histologic transformation and guide timely clinical intervention.
Medical subject headings
- Fluorodeoxyglucose F18
- Lymphoma, Large B-Cell, Diffuse
- Positron Emission Tomography Computed Tomography
- Lymphoma, B-Cell, Marginal Zone
- Stomach Neoplasms
- Cell Transformation, Neoplastic