Bone marrow aspirate concentrate adjunct for acetabular labral tear repair: a systematic review and meta-analysis.

Abstract

The objective of this study was to determine the effect of bone marrow aspirate concentrate (BMAC) on long-term patient outcomes when used as an adjuvant to acetabular repair of the labrum. A systematic review and meta-analysis were completed following PRISMA 2020 guidelines. Included in the analysis were controlled studies which assessed functional outcomes via the International Hip Outcome Tool-33 (iHOT-33) 12 or 24 months after acetabular repair with BMAC adjunct. 4 studies totaling 315 participants were analysed. Pooled effect sizes for iHOT-33 scores were not significantly different between control and treatment groups at 12 (<i>p</i> <i>=</i> 0.14, Cohen's D ≏ 0.79) or 24 months (<i>p</i> <i>=</i> 0.30, Cohen's D ≏ 0.56). Non-significant trends in favour of BMAC augmentation were found in this study. However, the trends reported are promising and warrant further investigation with further randomised controlled trials.