Reaching for more: How reproduction transforms the maternal intestine.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40378833.
- Also identified by DOI 10.1016/j.cell.2025.04.024.
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Abstract
Several organs undergo changes during pregnancy to accommodate fetal growth, including the small intestine. However, the signals that trigger this intestinal remodeling are not well understood. In a recent study, Ameku et al. describe an anticipatory intestinal growth program that is partially irreversible and supported by SGLT3a-dependent increase of Fgfbp1-positive progenitor cells.
Medical subject headings
- Intestines
- Reproduction
- Intestine, Small