Chronic Alteration in Cerebral FDG Metabolism After MRI-guided HIFU for Essential Tremor: A Clinical Case With PET and MRI Correlation.
case_report · Level V
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- Also identified by DOI 10.1097/RLU.0000000000005987.
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Abstract
A 74-year-old man with a history of monoclonal gammopathy of undetermined significance (MGUS) underwent surveillance whole-body 18 F-FDG PET 2 weeks before MRI-guided high-intensity focused ultrasound (MRgHIFU) of the left dentato-rubro-thalamic tract (DRTT) for his right-hand dominant, debilitating essential tremor. This baseline FDG PET showed normal thalamic metabolism. At 12 months post-treatment, FDG PET scan revealed a small focus of left thalamic hypometabolism, which corresponded to the left DRTT ablation area seen on post-treatment MRI. The patient was tremor-free in his right hand at 1-year follow-up. This case documents the chronic effects of MRgHIFU on cerebral FDG metabolism.
Medical subject headings
- Essential Tremor
- Positron-Emission Tomography
- Fluorodeoxyglucose F18
- Magnetic Resonance Imaging
- High-Intensity Focused Ultrasound Ablation
- Multimodal Imaging