Cognitive Outcome in Young Adults after Resolution of Epilepsy in Childhood.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 40401928.
- Also identified by DOI 10.1002/ana.27258 and PMC identifier 12174746.
- Licence recorded as CC BY-NC-ND.
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Abstract
Self-limited epilepsies of childhood are common and were considered benign. We aim to determine whether cognitive function in young adults who experienced epilepsy as children and are subsequently seizure-free and unmedicated differ from the general population. We report on a cross-sectional population-based study including 2,124,871 men and women aged 16-19 years. Participants > 5 years following the last seizure and > 2 years without anti-seizure medication (n = 3,452) had an odds ratio (OR) of having low cognitive function of 1.44 (95% confidence interval [CI] = 1.24-1.68, p < 0.001) using a multinominal regression model. Our results underscore the need to avoid the term "benign" in the classification of childhood epilepsies. ANN NEUROL 2025;98:62-66.
Medical subject headings
- Epilepsy
- Cognition
- Cognitive Dysfunction