Racial and ethnic differences in prescribing antihyperglycemic medications to persons with type 2 diabetes: An all of us cohort study.

Brady, Veronica J; Akyirem, Samuel; Padhye, Nikhil · Prim Care Diabetes · 2025

cross_sectional · Level IV

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Abstract

This study aimed to determine prescribing patterns for newer antihyperglycemic agents among racial and ethnic minorities with type 2 diabetes (T2DM) using the All of Us study data. We conducted a cross-sectional analysis of electronic health records (EHR) data obtained from the All of Us research study data. We included data from 20,016 persons with T2DM. Participants were eligible for the study if they were 18 years or older, living with T2DM, and had complete data on all variables of interest. Participants in the study were more likely to be > 55 years of age, identify as female, and non-Hispanic White. Nearly half of the participants were married or partnered and had a household income of less than $35,000 annually. Most participants had hypertension and obesity. Non-Hispanic Blacks had 14 % less odds of having a current or previous prescription of SGLT-2i and 28 % lower odds of receiving a prescription for a GLP-1RA. Despite known benefits to mitigating the risk for cardiorenal complications related to diabetes, there continue to be disparities in the prescribing of newer antihyperglycemic medications for racial and ethnic minorities.

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