Monoclonal antibody therapy for PCOS?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 40466621.
- Also identified by DOI 10.1016/j.cmet.2025.05.002 and PMC identifier 12994388.
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Abstract
There is no cure for polycystic ovary syndrome (PCOS), only treatment for its highly prevalent reproductive, cardiometabolic, and psychological symptoms. Early signs of PCOS appear during infancy. This enabled Cotellessa et al.<sup>1</sup> to develop and administer neutralizing antibody therapy during infancy in a female mouse model to eradicate PCOS symptomology.
Medical subject headings
- Polycystic Ovary Syndrome
- Antibodies, Monoclonal
- Antibodies, Neutralizing