Phosphaturic Mesenchymal Tumor in the Foot Detected by 99m Tc-FAPI-46 SPECT/CT and 18 F-FDG PET/CT.
case_report · Level V
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- Record sourced from PubMed, PMID 40472271.
- Also identified by DOI 10.1097/RLU.0000000000006016.
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Abstract
A 58-year-old woman presented with disabling bone pain and muscle weakness. Laboratory tests were unremarkable, except for decreased serum phosphate and elevated urine phosphate levels. A 99m Tc-MDP scan revealed multiple sites of bone fractures. Both 18 F-FDG PET/CT and 99m Tc-FAPI-46 scans identified a lesion in the left heel, which was later resected and diagnosed as phosphaturic mesenchymal tumor on pathologic evaluation. This case represents a pioneering experience in utilizing FAPI for detecting the origin of tumor-induced osteomalacia. It underscores the potential utility of various radiopharmaceuticals in the diagnostic workup of these patients.
Medical subject headings
- Fluorodeoxyglucose F18
- Positron Emission Tomography Computed Tomography
- Mesenchymoma
- Foot
- Single Photon Emission Computed Tomography Computed Tomography