Atypical Lymphoid Hyperplasia of the Liver on FDG PET/CT.

Tan, Xiaoxue; Liu, Yuegao; Wang, Yanli; Zhu, Yuzhao · Clin Nucl Med · 2025

case_report · Level V

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Abstract

Hepatic atypical lymphoid hyperplasia is a rare borderline lymphoproliferative lesion. Unlike benign reactive lymphoid hyperplasia, atypical lymphoid hyperplasia has the potential to transform into lymphoma. We describe MRI and FDG PET/CT findings in a case of hepatic atypical lymphoid hyperplasia. The hepatic lesion appeared as a small solid mass with central necrosis and low-grade enhancement on MRI and showed intense FDG uptake with SUV max of 8.2, mimicking malignancy. This case suggests that hepatic atypical lymphoid hyperplasia should be considered as a rare differential diagnosis in patients with focal hypermetabolic hepatic lesions.

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