Localization of Parathyroid Adenoma With 68 Ga-NODAGA-RGD PET/CT and Demonstration of "Metabolic Superscan" With Lincoln Sign and Costochondral Junction Beading : A Potential Clinical Application.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 40472287.
- Also identified by DOI 10.1097/RLU.0000000000006013.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
In primary hyperparathyroidism (PHPT), exact preoperative localization of parathyroid adenomas is essential for best surgical planning. While new PET tracers like 18 F-fluorocholine and 68 Ga-Trivehexin show promise, traditional imaging consists of 99m Tc-Sestamibi scintigraphy, SPECT/CT, and 4DCT. Herein, we report the potential new application of another angiogenesis imaging agent, 68 Ga-NODAGA-RGD PET/CT, illustrated in a 12-year-old girl with PHPT. The scan revealed diffuse skeletal tracer uptake (superscan) in addition to localizing right inferior parathyroid adenoma, thereby indicating systemic effects. This case underscores 68 Ga-RGD PET/CT as a possible instrument for parathyroid imaging and systemic evaluation, justifying more research to define its diagnostic value and role in treatment response evaluation.
Medical subject headings
- Parathyroid Neoplasms
- Positron Emission Tomography Computed Tomography
- Adenoma